eighteenth-century philosophy and twentieth-century science

Please answer the following question:
In the combined wake of eighteenth-century philosophy and twentieth-century science, the modern mind was left free of absolutes, but also disconcertingly free of any solid ground.” What were the factors determining the shift of the paradigm? What was valuable about it and what was dangerous about it? How does this shift of thought, from the absolutes towards uncertainty, prevail in the world today?

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